Emerging regulatory role of lncRNA MALAT1 in bone homeostasis: from the β–catenin–OPG/Jagged1 signalling axis to a broader regulatory network
In recent years, metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) has emerged as a candidate regulator of bone homeostasis, with reported effects on the differentiation, activity and communication of osteoblasts and osteoclasts. These effects are cell-type specific, and in some experimental models they a...