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Oct 2026

Tumor-derived amyloid-β drives TREM2+ macrophages immunosuppression in cholangiocarcinoma.

Cholangiocarcinoma (CCA) is an aggressive malignancy with limited therapeutic options. In this study, we explored the role of TREM2+ tumor-associated macrophages (TAMs) in modulating the immune microenvironment and their impact on anti-PD-1 therapy. Using single-cell RNA sequencing data and immunohistochemical analysis...

Xian-Ying Li, Rui-Kun Qian, Yi-Chun Li et al. · 0 citations
Open access Aug 2026

Toward safer digital sexual health communication: evaluating the public health reliability of large language model responses on sexually transmitted infections

This is the first study to quantify destigmatizing language as an explicit evaluation dimension for LLM-generated STI content, albeit as an exploratory measure pending formal content validation.

Shu-Cheng Zhang, Shuo Wang, Xiao-Yue Sun et al. · 0 citations

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