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Open access Oct 2026

Rifaximin ameliorates memory impairment and Alzheimer's pathological changes in APP/PS1 mice associated with changes in the gut microbiome-bile acids-serum metabolites networks.

BACKGROUND AND PURPOSE Modifying the brain-gut-microbiota axis has emerged as a promising therapeutic strategy against Alzheimer's disease (AD). Whether rifaximin, a non-absorbed and non-systemic antibiotic, can be applied to the treatment of AD remains unexplored. In this study, we investigated the effects of rifaximi...

Di Wu, Mei-Tong Nie, Ji-Xian Lin et al. · 0 citations
Open access Jul 2026

An interpretable clinical-proteomic framework identifies baseline neuroinflammatory proteomic patterns associated with post-thrombectomy mortality.

It is suggested that poor outcomes after EVT are associated with candidate baseline inflammatory and tissue-structure-related proteomic patterns, which provides a neuroinflammation-focused framework for hypothesis generation and candidate prioritization.

Min Xiao, Niu Qiao, Ruihong Zhang et al. · 0 citations

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