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Author

Yang Shi

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Review Sep 2026

TP53/p53 alterations in thyroid cancer: dedifferentiation, radioiodine refractoriness and risk stratification.

Most thyroid cancers are differentiated tumours with favourable outcomes, but a clinically important minority develops invasion, distant metastasis, loss of radioiodine uptake and histological dedifferentiation. TP53 encodes p53, a tumour suppressor that coordinates DNA-damage responses, cell-cycle arrest, apoptosis an...

Yang Shi, Jia-Peng Huang, W. Dong et al. · 0 citations

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