lncRNA TUG1 mediates palmitic acid-induced neuronal lipotoxic injury via the miR-449a-5p/caspase-3 and Akt/GSK-3β axes
A close relationship exists between excessive lipids and structural and functional brain dysfunction, with the long non-coding (lncRNA)-microRNA (miR)-mRNA network having an emerging role. Given the increasingly recognized role of the lncRNA taurine upregulated gene 1 (TUG1) in metabolic and neurodegenerative diseases,...