Author

Yang Wang

2 papers indexed here

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Open access Sep 2026

RBM25 Drives Hepatocellular Carcinoma Progression by Stabilizing YAP Through Regulating Oncogenic Splicing‐switch of MYPT1

ABSTRACT Deregulated alternative splicing (AS) is a hallmark of hepatocellular carcinoma (HCC), yet the specific splicing factors driving oncogenic programs remain largely uncharacterized. Here, we identify RNA‐binding motif protein 25 (RBM25) as a potent oncogenic driver that is overexpressed in HCC and correlates wit...

Wen-Jing Zhang, Li-Li Zhi, Tian Huang et al. · Advancement of science · 0 citations

Sep 2026

HNRNPK Lactylation Amplifies Inflammation and Exacerbates Myocardial Ischemia/Reperfusion Injury by Regulating Jag2 Splicing.

BACKGROUND Myocardial ischemia/reperfusion injury triggers profound metabolic reprogramming and lactate accumulation. However, how this metabolic stress regulates inflammatory gene expression remains poorly understood. We hypothesized that lactylation, a lactate-derived posttranslational modification, links metabolic s...

Su-Yun Chen, Si-Man Shen, Wen-Mei Su et al. · Circulation · 0 citations