Aug 2026
ALK regulates macrophage polarization via the USP7/SOX9/MFAP2-mediated glycolytic pathway to promote neuroblastoma progression.
Findings identify the ALK/USP7/SOX9/MFAP2 cascade as a critical regulator of metabolic reprogramming and immune evasion in NB, and suggest that targeting this axis may represent a promising therapeutic strategy for high-risk NB.
C. Lai, Kun-Ting Xu, Renfu Li et al.
· Cellular Signalling · 0 citations