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Review Sep 2026

Deubiquitinases in mitophagy: therapeutic control of mitochondrial quality.

Mitochondrial quality control is essential for maintaining cellular and tissue homeostasis. Mitophagy, the selective autophagic removal of damaged mitochondria, is a central component of this process, and defects in mitophagy are increasingly linked to neurodegeneration, cardiovascular disease, cancer, and inherited mi...

Yang Xu, Bahareh Behrouz, Andrew Lee et al. · 0 citations
Open access Aug 2026

Deep-learning-enabled multi-omics analyses for prediction of future metastasis in cancer

Metastasis remains the leading cause of cancer-related mortality, yet predicting future metastasis is a major clinical challenge due to the lack of validated biomarkers and effective assessment methods. Here, we present EmitGCL, a deep-learning framework that accurately predicts future metastasis and its corresponding...

Xiaoying Wang, Maoteng Duan, Anthony J. Snyder et al. · 0 citations

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