Macrophage-Targeted Cyclodextrin-Based Metal-Organic Frameworks Restore Redox-Efferocytosis Coupling to Promote Osteochondral Repair in Temporomandibular Joint Osteoarthritis.
Temporomandibular joint osteoarthritis (TMJOA) causes cartilage degeneration and jaw dysfunction, yet current treatments mainly provide symptomatic relief rather than restore the diseased joint microenvironment. Although suppressing ROS-driven oxidative stress is essential for limiting inflammatory injury, impaired cle...