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Yang-Yang Yu

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Review Oct 2026

Understanding the roles of interleukin-33: is there promise for therapeutic targeting?

INTRODUCTION IL-33 is a chromatin-associated alarmin of the IL-1 cytokine family involved in tissue homeostasis and immune responses following epithelial or endothelial injury. Although the IL-33/ST2 axis is an attractive therapeutic target, clinical outcomes with IL-33- or ST2-directed agents have varied across diseas...

Xiu-Zhu Gao, Yang-Yang Yu, Shao-Ling Zhong et al. · 0 citations

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