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Author

Yang Zhang

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Open access Sep 2026

Celastrol Attenuates Doxorubicin-Induced Heart Failure by Preserving Mitochondrial Integrity and Suppressing Oxidative Stress and Is Accompanied by Changes in Gut Microbiota

Background/Objectives: Doxorubicin (DOX) is an effective chemotherapeutic agent whose clinical use is limited by dose-dependent cardiotoxicity that may progress to irreversible heart failure. Celastrol (Cel), a bioactive triterpenoid from Tripterygium wilfordii, has recognized anti-inflammatory and antioxidant activiti...

Yang Zhang, Jing-Yi Qi, Ming-Yang Cui et al. · 0 citations

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