TRIM59 attenuates sleep disturbances and improves hippocampal neuronal injury in PCPA-induced sleep-deprived male mice via the NLRP3 signaling pathway.
Although TRIM59 has been reported to exert neuroprotective effects against brain injury, its role and underlying mechanisms in sleep disturbances remain unclear. This study aimed to elucidate the effect of Tripartite Motif Containing 59 (TRIM59) on sleep disorders and the associated hippocampal damage and cognitive dys...