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Author

Yang Zhou

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Sep 2026

Design, Synthesis, and Antimicrobial Activity of Novel Cyt- bd Inhibitors Targeting Energy Compensation in Mycobacterium tuberculosis

This study supports co-targeting Cyt-bd and Cyt-bcc as a therapeutic strategy for drug-resistant tuberculosis by finding a structure–activity relationship study starting from the previously identified Cyt-bd inhibitor 12, leading to the discovery of 17aa (YH-685).

Qiao Qin, Zhuo-Heng Liu, Chen-Yi Cheung et al. · 0 citations
#quantum computing Open access Nov 2025

Macrocycle-DB: a comprehensive database for macrocycle-based drug discovery

Macrocycle-DB is presented, the most extensive online database dedicated to macrocycles, featuring 45 525 compounds, including 76 approved drugs and 105 clinical candidates that target 2533 proteins.

Minchuan Jiang, Tianyu Liu, Muzammal Hussain et al. · 6 citations

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