Author

Yang Zhu

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Open access Oct 2026

Tebuconazole-induced ferroptosis impairs human trophoblast function via GPX4: A multi-omics study on unexplained recurrent pregnancy loss.

Tebuconazole (TEB) is a widely used triazole fungicide with suspected endocrine-disrupting and reproductive toxicity. However, its effects on human placental trophoblasts and its association with unexplained recurrent pregnancy loss (RPL) remain poorly defined. Chorionic villi from 27 women with unexplained RPL and 25...

Shao-Wei Wang, Hui-Yi Che, Xi-Ya Ren et al. · Ecotoxicology and Environmen... · 0 citations

Open access Aug 2026

Industrial phenolic compounds targeting 11β-hydroxysteroid dehydrogenase 2: A comparative in silico and structure-activity investigation in humans and rats.

Industrial phenolic compounds (IPCs) are widespread environmental contaminants with known endocrine-disrupting potential. This study aimed to investigate the inhibition of 13 IPCs on human and rat 11β-hydroxysteroid dehydrogenase 2 (11β-HSD2), a crucial enzyme responsible for cortisol inactivation. The inhibitory poten...

Lu-Bin Xie, Lei Shi, Yun-Bing Tang et al. · Ecotoxicology and Environmen... · 0 citations