Targeting the extracellular vesicle-immune axis in prostate cancer: mechanisms of immune evasion and emerging therapeutic strategies.
Prostate cancer is one of the least immunogenic malignancies and poorly responds to immunotherapies. Characterized by an immunosuppressive tumor microenvironment and a scarcity of cytotoxic T-cell infiltrates, prostate cancer has been closely linked to extracellular vesicles (EVs), including exosomes and microvesicles,...