Metabolic and inflammatory traits and depression: a Mendelian randomization study with late-adolescent population-based and clinical triangulation
Objective Metabolic dysfunction and systemic inflammation have been associated with adolescent depression, but their causal relevance remains uncertain. We examined whether insulin resistance, proxied by the triglyceride-glucose (TyG) index, and high-sensitivity C-reactive protein (hs-CRP) show genetically proxied asso...