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Author

Yanyan Wang

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Review Open access Aug 2026

Brain O-GlcNAcylation in Neurodegenerative Diseases: Context-Dependent Mechanisms and Precision Therapeutic Translation

Highlights What are the main findings? O-GlcNAcylation exerts context-dependent effects in neurodegenerative diseases rather than being uniformly protective or detrimental. We propose a state-resolved framework integrating disease stage, cell type, subcellular localization, substrate specificity, and therapeutic interv...

Shao-Shuai Lu, Zi-Yang Chen, Yanyan Wang et al. · 0 citations

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