The subgranular zone (SGZ) of the hippocampus represents a principal site of adult neurogenesis and exhibits distinct structural and organizational features. Increasing evidence indicates that neural stem cell (NSC) behavior in the SGZ is not solely determined by intrinsic cellular properties, but is critically shaped...
Teng-Yu Zhao, Yu-Han Zhou, Peng-Yu Pan et al.· Frontiers in Cellular Neuros...· 0 citations
A organelle-centered perspective will clarify AD pathogenesis and help guide the development of next-generation neuroprotective therapies, and highlight the essential requirements for building one, centered on synaptic mitochondrial bioenergetics and quality control.
Yu-Xin Wang, Wei-Dong Wu, Li-Shuang Yan et al.· Frontiers in Pharmacology· 0 citations
AD is a complex neurodegenerative disorder characterized by chronic neuroinflammation. Microglia, the brain’s resident immune cells, centrally regulate AD pathophysiology. Recent studies have highlighted microglial mitophagy as an important interface linking mitochondrial quality control to innate immune responses.Inta...
Ming-Yue Zou, Teng-Yu Zhao, Wei-Dong Wu et al.· Journal of Neuroinflammation· 0 citations
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