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Open access Oct 2026

Super‐Resolution MRI–Derived Tumor‐Stroma Ratio Phenotyping for Prognostic and Therapeutic Stratification in Pancreatic Ductal Adenocarcinoma

ABSTRACT Pancreatic ductal adenocarcinoma (PDAC) exhibits profound stromal heterogeneity that influences tumor progression, recurrence risk, and therapeutic response; however, stromal phenotypes are currently assessed by postoperative histopathology. Here, we developed a super‐resolution MRI (srMRI)–based radiomics mod...

Xing-Xing Wang, Zong-Yu Xie, Han Li et al. · 0 citations
Jul 2026

Topological imaging of single-cell CAF heterogeneity for predicting prognosis and adjuvant chemotherapy benefit in pancreatic cancer.

By translating adverse CAF subpopulation signatures into a CT-based topological biomarker, ra-CAPR enables individualized preoperative risk stratification and may facilitate risk-adapted postoperative management.

Ling-Ling Wang, Zong-Yu Xie, Qi-Ying Tang et al. · 0 citations

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