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Aug 2026

Environmental Endocrine Disruptors Activate CBX2 to Disrupt Cholesterol Homeostasis in PCOS.

Polycystic ovary syndrome (PCOS) is a common endocrine disorder influenced by genetic and environmental factors, yet the molecular mechanisms linking endocrine-disrupting chemicals (EDCs) to ovarian dysfunction remain unclear. Here, we establish a letrozole-induced PCOS-like rat model and integrate bulk RNA-seq, single...

Chan Zhu, Xian-Liang Qiu, Hong Yang et al. · 0 citations

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