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Open access Sep 2026

Osteoimmune senescence in aging bone: from inflammaging dogma to cell-type-specific therapeutic windows

Aging-related bone diseases are often interpreted through hormonal decline, defective remodeling, and chronic low-grade inflammation, yet these accounts do not fully capture the cellular, spatial, and temporal heterogeneity of skeletal aging. Bone is an immune-active organ sustained by coordinated signaling among skele...

Lan Zhang, Yao Yao, Jin-Xu Chen · 0 citations
Review Open access Aug 2026

From Cloning Vectors to Phage Display: Engineering Principles and Translational Applications of Bacteriophage Display Platforms

Bacteriophage technologies have evolved from classical cloning vectors into programmable platforms for genome engineering and molecular selection. Phage display couples a surface-presented binding phenotype to its encoding genotype, enabling iterative selection, sequence recovery, and optimization of peptides, antibody...

Tingting Hong, Nan Chen, Yingli Yang et al. · 1 citation
Review Jul 2026

Programmed cell death in autoimmune diseases.

Autoimmune diseases (AIDs) are chronic inflammatory disorders in which loss of self-tolerance intersects with tissue stress and damage. Increasing evidence indicates that regulated cell death (RCD) can act as an upstream amplifier in selected autoimmune settings, while in other settings it may mainly report downstream...

Xiaoyu Cai, Yao Yao · 0 citations

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