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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Yaohui Nie

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Open access Jul 2026

Discovery and Characterization of a Potent and Selective Oral Inhibitor of STAT6 for the Treatment of Allergic Diseases 2257118

STAT6 is a transcription factor downstream of IL-4 and IL-13 signaling that acts as a key driver of type 2 inflammation, which is associated with atopic dermatitis and asthma. Inhibition of the IL-4/IL-13 pathway is clinically validated for treatment of allergic diseases. Our aim is to develop an oral small molec...

K. Garlick, J. Sweeney, M. Chau et al. · 0 citations

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