Yaqeen A. Jlood

Design, synthesis, molecular docking, and anticancer and antibacterial evaluation of new Schiff bases of thiadiazole derivatives targeting cellular mesenchymal-epithelial transition tyrosine kinase

Several new nitrogenous heterocyclic Schiff base derivatives (2a-2e) were synthesized by the reaction of 5-amino-1,3,4-thiadiazole-2-thiol with various aldehydes. Molecular docking against cellular mesenchymal-epithelial transition tyrosine kinase demonstrated favorable binding interactions for the prepared compounds,...