Yaroslav D. Shansky

A multi-step screening algorithm for fecal microbiota transplantation donors: integrating metagenomic and metabolomic profiling for improved safety and donor quality assessment

Background Fecal Microbiota Transplantation (FMT) has emerged as a highly effective treatment for recurrent Clostridioides difficile infection. It is also a promising therapeutic approach for other microbiome-related disorders. However, the safety and efficacy of FMT depend critically on rigorous donor screening and se...