Author

Yaxi Du

2 papers indexed here

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Open access Sep 2026

A Lynch Syndrome Family With Germline MLH1 c.931A>G Showing Preserved Tumor MMR Immunostaining but MSI‐H Status: A Case Report

ABSTRACT Lynch syndrome screening may be complicated by discordant tumor testing results. We report a family carrying the germline MLH1 c.931A>G (p.Lys311Glu) variant in which both the proband and his father had colorectal tumors with retained mismatch repair protein expression by immunohistochemistry but microsatellit...

Jing-Jing Cai, Zhuo-Ying Li, Ting-Ting Han et al. · Clinical Case Reports · 0 citations

Aug 2026

ACOD1 enhances the ferroptosis resistance of tumor-associated macrophages through the KEAP1/NRF2 axis and promotes triple-negative breast cancer progression.

BACKGROUND Tumor-associated macrophages (TAMs), as core components of the triple-negative breast cancer (TNBC) tumor microenvironment (TME), can promote tumor progression. Ferroptosis has been shown to be involved in TNBC progression, but its regulatory mechanisms in TNBC TAMs remain incompletely understood. METHODS...

Jie Yang, Xiyin Li, Xin Qu et al. · Pathology, Research and Prac... · 0 citations