COL1A1 modulates apatinib sensitivity through promoting glycolysis and angiogenesis in gastric cancer cells.
BACKGROUND Our previous bioinformatic study identified Collagen type I alpha 1 chain (COL1A1) as a candidate regulator associated with gastric cancer (GC) progression and response to anti-angiogenic therapy. However, whether COL1A1 influences the sensitivity of GC cells to apatinib and the underlying mechanisms remains...