Yellamandayya Vadlamudi

Microglia statuses in Alzheimer’s disease and lessons from anti-tumor microglia

Alzheimer’s disease (AD) and related dementias are closely associated with alterations in microglial states. These microglial changes occur in response to amyloid-β (Aβ) accumulation and aberrant tau phosphorylation and can either protect against or exacerbate AD progression, depending on factors such as disease stage,...