Minimal Functional Scaffolds of the Streptococcus sinensis Competence-Stimulating Peptide Define the Balance between Receptor Promiscuity and Signaling Specificity.
Quorum sensing (QS) enables bacteria to coordinate collective behaviors through the detection of secreted signaling molecules and represents an attractive target for anti-virulence therapeutic development. In Streptococcus sinensis, an emerging opportunistic pathogen associated with infective endocarditis, QS is mediat...