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Yi-Chen Zhou

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Review Open access Sep 2026

Neural Circuit Mechanisms of Disorders of Consciousness and Potential Therapeutic Targets of Brain Stimulation

ABSTRACT Background Disorders of consciousness (DoC) lack an integrated framework to guide neuromodulation. This review updates three hierarchical frameworks—ARAS, mesocircuit, and ICNs—and maps therapeutic targets within each. Methods We synthesized recent neuroanatomical, optogenetic, neuroimaging, and clinical trial...

Yi-Chen Zhou, Tian-Qing Cao, Si-Peng Zhu et al. · 0 citations

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