Yi-Cheng Li

METTL4 knockout alleviates sepsis-induced liver injury via inhibiting NCOA4-mediated ferritinophagy and ferroptosis.

The liver represents a primary target organ frequently compromised during the progression of sepsis. Ferroptosis is a distinct mode of regulated cell death driven by iron-dependent lipid peroxidation, which has been identified as being involved in the pathogenesis of sepsis-induced hepatic dysfunction. However, the reg...