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Author

Yi-Cheng Tsai

2 papers indexed here

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Aug 2026

Liquid biopsy-based detection of circulating and exfoliated cholangiocarcinoma tumor cells from blood and bile using heparan sulfate octasaccharides on integrated microfluidic systems.

Early diagnosis of cholangiocarcinoma (CCA) remains challenging because existing diagnostic approaches often lack sufficient sensitivity for reliable detection of early-stage disease. Circulating tumor cells (CTCs) in blood and exfoliated tumor cells (ETCs) in bile represent valuable targets for liquid biopsy-based det...

Wei-Chun Tsai, Anandaraju Bandaru, Cheng-Hsiu Chang et al. · 0 citations
Oct 2026

An integrated microfluidic platform for tunable-stringency competitive affinity selection of folate receptor alpha aptamers.

This study developed a new microfluidic device for competitive affinity selection of single-stranded DNA (ssDNA) aptamers targeting folate receptor alpha (FRα), an ovarian cancer (OvCa) biomarker. The device integrated micropumps, microvalves, and micromixers to automate four selection rounds in ∼2.5 h, while washing s...

Yi-Da Chung, Yi-Cheng Tsai, Keng-Fu Hsu et al. · 0 citations

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