Yi-Dong Zhou

Global, Regional, and National Burden of Early-Onset Breast Cancer in Women, 1990–2021: GBD 2021 Analysis of Trends, Modifiable Risk Factors, and Health Inequalities

Background Early-onset breast cancer (EOBC) affects women aged 15–44 years during reproductive and economically active life stages. We quantified global, regional, and national EOBC burden from 1990 to 2021, including temporal inflection points, modifiable risks, and health inequalities. Methods Using Global Burden of...

Breast Modular Resection Surgery Teaching Model Improves the Effect of Teaching Under Regional Anesthesia for Breast Conserving Surgery and Sentinel Lymph Node Biopsy in Day Surgery

ABSTRACT Background Breast‐conserving surgery (BCS) combined with sentinel lymph node biopsy (SLNB) is a standard treatment for early‐stage breast cancer. However, surgical variability and patient discomfort under regional anesthesia present challenges for training programs and consistent clinical outcomes. To address...

CircExor enables interpretable prediction of circRNA localization into extracellular vesicles.

Benzophenone-3 promotes luminal breast cancer progression via activation of the ERα/E2F1/RPA3 axis.

It is reported that BP3 exposure potently stimulates both proliferative and migratory capacities of BC cells, concomitantly accelerating the acquisition of aggressive malignant traits.

T-Cell Exhaustion and Senescence in Cancer: Regulatory Circuits and Therapeutic State Engineering.

This mechanistic view shifts the therapeutic question from how broadly to activate T cells to which states should be generated, preserved, or rescued and provides a testable basis for state-informed biomarker development and therapeutic design.

Association of serum folate levels with mortality among cancer survivors: insights from NHANES 1999-2018.

Lower serum folate levels were associated with increased mortality among cancer survivors and the findings suggest a non-linear pattern, with more favorable outcomes at intermediate folate levels and no additional benefit at higher levels.