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Author

Yi-Fan Cao

2 papers indexed here

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Open access Aug 2026

GULP1 Fuels Resistance to PD-1 Blockade through Lipid-Mediated Metabolic Reprogramming of Tumor-Associated Macrophages in Gastric Cancer

Background: Immune checkpoint inhibitors targeting programmed cell death protein 1 (PD-1) have substantially improved the treatment of multiple cancers; however, only a small proportion of gastric cancer (GC) patients achieve durable clinical benefit. The underlying tumor-intrinsic mechanisms driving resistance to anti...

Zi-Hao Zhang, Wenxin Xu, Kuan Yu et al. · 0 citations
Open access Sep 2026

M2 macrophage-derived exosomes and miR-132-3p promote gastric cancer cell aggressiveness and attenuate ferroptosis-related changes

This study aimed to explore the correlation between the ability of M2-type tumor-correlated macrophage-derived exosomes (EXOs) to trigger the aggressiveness of gastric cancer (GC) cells and the miR-132-3p expression. EXOs were isolated from the conditioned media of M0 and M2 macrophages and characterized by...

Tao Zhang, Yong Huang, Peng Cheng et al. · 0 citations

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