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Open access Aug 2026

Lymphangiogenesis-related gene signature–based risk model for prognostic assessment of cervical cancer: immune–metabolic characterization and molecular subtype analysis

Background Lymphangiogenesis promotes tumor dissemination and may shape the immune contexture of cervical cancer, yet lymphangiogenesis-related prognostic stratification and its immunometabolic implications remain insufficiently defined in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC). Methods...

Xi-Jing Fan, L. Chen, Jing Xu et al. · 0 citations
Open access Aug 2026

Senescence-related immunosuppressive gene MFAP2 orchestrates stromal-immune crosstalk and immunotherapy resistance in gastric cancer

MFAP2 is a hub SRIG linking eCAFs, ECM remodeling, and immune escape in GC, which serves as a reliable prognostic and ICI resistance predictor and potential therapeutic target, providing a basis for precision therapy in GC.

Yi-Chan Hu, Liao-Xiang Zhu, Lijun Zhou et al. · 0 citations

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