A hypoxia-derived seven-gene signature reflects immune remodeling in diabetic kidney disease: integrated transcriptomic analysis and experimental validation.
AIMS To develop and assess a hypoxia-associated gene signature for diabetic kidney disease (DKD), and to examine its relationship with immune remodeling and molecular heterogeneity. METHODS GEO renal transcriptomic datasets were integrated to identify hypoxia-related differentially expressed genes. Weighted gene co-e...