MFN2-mediated remodelling of ER-mitochondria communication alleviates ochratoxin A-induced hepatocyte ferroptosis by enhancing mitophagy.
Mycotoxins are ubiquitous environmental contaminants that widely occur throughout ecosystems and the food chain, posing persistent threats to environmental safety and public health. Ochratoxin A (OTA) is a widespread and chemically stable mycotoxin with recognized hepatotoxicity, yet the mechanisms linking OTA exposure...