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Open access Sep 2026

Phenotypic age metrics for risk stratification of chronic disease burden and all-cause mortality in adults

Phenotypic age gap (PAG) and phenotypic age acceleration (PhenoAgeAccel) are measures of biological ageing that have been linked to adverse health outcomes. However, their relationships with common chronic diseases and mortality in nationally representative populations remain incompletely understood. We investigated th...

Zi-Hao Wang, Xin-Ru Zhong, Yu-Zhou Cai et al. · 0 citations

Annotation-Guided Temporal Attention with a Sleep Foundation Model for Predicting Future Cognitive Impairment from Polysomnography

A complete prediction pipeline was developed that used a frozen SleepFM encoder for five-minute PSG segments, a bidirectional LSTM for temporal modelling, and annotation-guided attention based on algorithmic sleep stages and events for future cognitive-impairment prediction.

Xiao-Yun Wang, Wei-Ping Liu, Yi-Xuan Zhang et al. · 0 citations

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