Open access
Aug 2026
The NE-adrenergic receptor axis drives osteoarthritis progression via neurovascular cross-talk: a dual-responsive hydrogel strategy.
Osteoarthritis (OA) progression is strongly driven by the dysregulated interplay between the sympathetic nerve and abnormal vascularization, severely affecting patients' physical and mental well-being. In this study, temporomandibular joint osteoarthritis (TMJ-OA) was induced in mice using a unilateral anterior crossbi...
Haoyan Zhao, Jia-Lu Gao, Weiwei Zhu et al.
· Journal of Controlled Releas... · 0 citations