Yi-Han Meng

Immunogenic cell death and tertiary lymphoid structures jointly define dysregulated antitumor immune states and therapeutic vulnerability in lung adenocarcinoma

Immunogenic cell death (ICD) and tertiary lymphoid structures (TLSs) are biologically distinct yet interconnected components of antitumor immunity. ICD promotes danger-associated immune activation, whereas TLSs organize local adaptive immune responses. However, how these processes jointly affect immune heterogeneit...