AZD6738 reverses the LPS-induced corneal inflammatory transcriptional program through a conserved transcription factor network converging on NF-κB
AZD6738 reverses a substantial part of the LPS-induced corneal inflammatory transcriptome and suppresses an inflammatory TF program whose regulons are conserved in human bacterial keratitis, supporting ATR inhibition as an adjunct to antimicrobial therapy in bacterial keratitis.