Sep 2026
GPR87 promotes DMBA/TPA-induced skin tumorigenesis through the YAP-SOX2 axis.
G protein-coupled receptor 87 (GPR87) has been implicated in the growth and progression of several malignancies, but its role in cutaneous squamous cell carcinoma (cSCC) remains poorly understood. Here, we found that GPR87 was aberrantly upregulated in murine and human skin tumors and in TPA-stimulated HaCaT keratinocy...
Biao Guo, Yi-Yi Liang, Xiao-Feng Qin et al.
· Carcinogenesis · 0 citations