Author

Yi-Jun Tang

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Open access Oct 2026

ANGPTL8 induces the aging of hematopoietic stem/progenitor cells

Hematopoiesis depends on the sustained function of hematopoietic stem and progenitor cells (HSPCs). However, aging progressively impairs HSPC function, contributing to immunosenescence, hematologic malignancies, and degenerative disorders. Therefore, elucidating the mechanisms underlying HSPC aging is essential for dev...

Mei-Juan Chen, Min Zhang, Han-Yi Mei et al. · Biogerontology (Dordrecht) · 0 citations

Open access Aug 2026

Desaminotyrosine Alleviates Hepatic Ischemia-Reperfusion Injury via the MAPK/Ferroptosis Axis and Bifidobacterium pseudolongum Modulation.

A novel microbial metabolite is revealed that improves hepatic I/R injury, clarify the inhibitory effect of DAT on ferroptosis, discover new therapeutic uses of DAT, and identify Bif as a potential novel probiotic for preventing liver I/R injury, providing new options for the preventive treatment of liver I/R injury.

Junyang Zhou, Man Luo, Ping Zhu et al. · Pharmacological Research · 0 citations