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Yi-Jun Wang

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Open access Jul 2026

Hypoxia tumor-associated macrophages facilitate hepatocellular carcinoma metastasis via uPA-uPAR pathway.

Hypoxia drives TAM heterogeneity in HCC via an H‑TAM‑intrinsic HIF‑1α-uPA axis that engages uPAR on HCC cells to promote metastasis, and dasatinib is a promising therapy to block this axis and improve outcomes.

Yi-Jun Wang, Xiaomin You, Xiangyuan Luo et al. · 0 citations

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