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Author

Yi-Lei Zhang

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Review Aug 2026

Bap1-mediated deubiquitination determines immune tolerance and anti-tumor immunity via modulating eTreg cell differentiation and ferroptosis.

This work identifies the histone deubiquitinating enzyme Bap1 as a pivotal regulator of eTreg cell fate via its H2A deubiquitination activity to maintain immune tolerance and restrains antitumor immunity.

Hai-Yan Liu, Yan-Hong Su, Danni Chen et al. · 0 citations
Review Open access Jul 2026

Tumor suppressor BAP1 emerges as a key regulator of metabolism and cell death in tumors

An integrated overview of the molecular features and functional roles of BAP1 is provided, with particular emphasis on its impacts on the regulation of cell death including apoptosis, ferroptosis and disulfidptosis.

Kexin Fan, Jun Yao, Shaobo Wu et al. · 0 citations

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