Optimizing vancomycin therapy: the critical role of dosing frequency, AUC monitoring and gender: a retrospective cohort study.
Background Optimizing vancomycin therapy requires balancing efficacy and toxicity. Although therapeutic drug monitoring (TDM) guided by area-under-the-curve (AUC) measurements is now recommended, the effect of dosing frequency and patient-specific factors remain underexplored. This study examined the relationships of d...