Real-Time Monitoring Ferroptosis-Mediated Drug-Induced Liver Injury Using a Near-Infrared Mitochondrial Viscosity Probe.
XT-TPE is reported, a mitochondrion-targeted near-infrared (NIR) "turn-on" viscosity probe based on a tetraphenylethylene (TPE)-xanthene hybrid that enables noninvasive hepatic viscosity imaging and establishes a new strategy for anti-DILI drug screening.