Author

Yilin Yang

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Open access Oct 2026

Monkeypox virus M2 rewires nucleocytoplasmic transport to coordinate host translation suppression and immune evasion

Host shutoff is a conserved viral strategy to dismantle cellular defenses, yet the molecular orchestrators in large DNA viruses remain poorly defined. Through a systematic functional screen of the monkeypox virus (MPXV) proteome, we identify M2 as a potent, multifunctional effector that executes a global blockade of ho...

Xin Huang, Yi-Lin Yang, Wei Wang et al. · bioRxiv · 0 citations

Open access Aug 2026

Enteric α-defensins contribute to intestinal mucosal immunity against SARS-CoV-2 infection.

It is suggested that enteric α-defensins help alleviate, as host protective factors, Covid-19 symptoms in the intestine despite higher ACE2 expression in the gut than in the lungs, and that Crp5 may be developed as a broad-spectrum antiviral for the treatment of coronavirus infection irrespective of virus type and vari...

Yilin Yang, Qianxi Yang, Xin Huang et al. · Mucosal Immunology · 0 citations