The therapeutic effect of radiotherapy is greatly hindered by radiation injury, primarily driven by a dysfunctional immune microenvironment. Macrophages play an essential role in regulating the radiation response, but their intrinsic mechanism is not fully understood. In this study, we aimed to identify key molecular...
Yong-Long Yu, Dong-Wei Guan, Yao-Ying Long et al.· Journal of Proteome Research· 0 citations
Introduction Natural killer cell alloreactivity contributes to the graft-versus-leukemia (GVL) effect of haploidentical hematopoietic stem cell transplantation (haplo-HSCT). However, its importance remains controversial across studies. Methods In this retrospective analysis, we studied NK cell alloreactivity and its as...
Xiangfeng Tang, Hai-Fei Zhou, Weijie Zhang et al.· Frontiers in Immunology· 0 citations
ABSTRACT Bone marrow fibrosis (MF) reflects stromal remodeling and has been associated with treatment resistance and adverse outcomes in hematologic malignancies; however, its clinical significance in acute lymphoblastic leukemia (ALL) remains uncertain. We retrospectively analyzed 103 patients with newly diagnosed ALL...
Ying Chen, Si-Heng Liu, Cen-Xia Ran et al.· Cancer Medicine· 0 citations
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