Median effective dose and 95% effective dose of oliceridine combined with ciprofol for painless gastroscopy: a dose-finding study based on Dixon’s up-and-down method
Objective To determine the median effective dose and estimate 95% effective dose of oliceridine combined with ciprofol for suppressing gastroscope insertion responses, stratified by sex. Methods This prospective, sex-stratified trial enrolled patients between 16 January and 31 March 2026, at the General Hospital of Nor...