Author

Yi-Ming Sun

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Open access Oct 2026

Metformin and atorvastatin ameliorate MASH via the AMPK/NF-κB pathway

Background Despite being a globally prevalent chronic liver disease, MASLD currently lacks any approved pharmacotherapy. MET and ATO individually confer benefits against MASLD, but their combined therapeutic effects have seldom been investigated. The current work aimed to verify the therapeutic benefits of their combin...

Bin Zhang, Na Li, Fang Liu et al. · Frontiers in Endocrinology · 0 citations

Open access Oct 2026

A biomimetic dual-targeting nanoplatform enhancing pyroptosis and chemosensitization for precision therapy of diffuse large b-cell lymphoma

To elucidate the role of SHP-2 in regulating pyroptosis through the TXNIP‑NLRP3 inflammasome axis in diffuse large B‑cell lymphoma (DLBCL) and to evaluate the therapeutic efficacy and safety of a SHP099‑loaded B‑cell membrane–CD20 aptamer dual‑targeting biomimetic nanoplatform (SHP099@Bmem‑AptCD20). SHP-2...

Jing-Xuan Lian, Xiao-Hui Duan, Wen-Jie Chen et al. · Journal of Nanobiotechnology · 0 citations